"Prednisone and other corticosteroid drugs don't just suppress uncomfortable itching and inflammation, they suppress the immune system as well. Add to this the possible long-term side effects of water retention, hypertension, liver damage, thyroid dysfunction, obesity, and heart attack. [Prednisone tablets or shots also cause some dogs to urinate excessively]..." (Tilford, Greg. "Herbs for Flea Relief." Whole Dog Journal, June 2003, 21-23).

Colby Glass, MLIS